Recent News

Multi-camera array microscope pre-print is out!

October 11, 2021

Please check out our first work that details a new gigapixel microscope technology:

New work details Fourier ptychography on SPAD arrays

September 21, 2021

Please check out Xi's new paper about implementing a computational imaging technique, termed Fourier ptychography, on a new type of single-photon detector array:

Noninvasive brain function detection effort

August 27, 2021

Check out a nice article here about our recent efforts with creating a new optical device to assist with epilepsy surgery planning:


We are hiring for postdocs and PhD students!

July 12, 2021

Interested in joining the Computational Optics Lab? We are hiring! Especially for postdoc roles. If interested, please reach out to Dr. Horstmeyer directly with any questions (

Dr. Horstmeyer receives Hartwell Individual Biomedical Research Award

April 12, 2021

The Computational Optics Lab is happy to announce that it will be funded by Hartwell Foundation's Individual Biomedical Research Award - Thank you to all of the researchers and clinicians who have helped [...]

Prof. Horstmeyer receives 3M Young Faculty Award!

March 18, 2021

This generous award from 3M will be used to continue our development of new computational and intelligent microscopes that can allow us to "see more" at high resolution!

Parallelized high-speed cortical blood flow detection - first paper published!

February 17, 2021

We have developed a new technique to detect blood flow and measure other small variations deep within tissue:

Articles about AI and pathology

January 25, 2021

Please read more about Duke's efforts to improve pathology, including our work on a smart microscope for automated pathology, in the following articles:

Deep learning for pupil and illumination paper published!

October 6, 2020

Congratulations to Kanghyun, Pavi and Colin and our collaborator Ron Appel on completing a nice new paper in Optics Letters!

COL awarded 2021 Duke Coulter Award

September 15, 2020

This new grant will fund our research efforts surrounding a portable "intelligent" microscope for rapid blood smear analysis. We'll be working closely with the Duke hospital over the next year to hopefully get some nice data in what should be an exciting project!

Congrats to Shiqi for Theo Pilkington Fellowship!

July 21, 2020

Shiqi was recently awarded a Theo Pilkington Fellowship for the upcoming year for his outstanding work as a PhD student - great job!!

Two new pre-print papers out!

July 12, 2020

Hot off the press - the Computational Optics Lab recently published two new papers that we're excited about:

Neurophotonics chapter is out

June 6, 2020

Our recent book chapter about wavefront engineering for imaging deep within the brain is now available [...]

Colin receives an NSERC Fellowship!

May 4, 2020

I'd like to congratulate Colin on receiving a fellowship from the Natural Sciences and Engineering Research Council of Canada, which will offer him some generous support for his research in our lab. Great job!

Kevin's new deep prior paper

April 18, 2020

Kevin's really interesting work, on improving the quality of 3D image reconstruction using a completely untrained deep learning network, is now published. Great job Kevin!

Congratulations Kanghyun!

March 24, 2020

Kanghyun Kim, a new PhD student in the lab, recently was awarded the prestigious John T. Chambers Fellowship from the Fitzpatrick Institute for Photonics (FIP) at Duke University - great job with all of your hard work!

Fourier ptychography review paper out!

March 20, 2020

We've just finished a comrehensive review paper on Fourier ptychography:

Rotating X-ray beams!

February 17, 2020

During a very fun and interesting collaboration with Dr. Lars Loetgoring from the Advanced Research Center for Nanolithography and Vrije Universiteit in Amsterdam, we helped suggest some new ways to create and characterize X-ray beams that rotate as they propagate.

Deep Image Prior for 3D imaging

December 24, 2019

Kevin's new paper is on using a "deep image prior" to improve the quality of 3D diffraction tomography reconstructions:

Machine Learning Microscope Paper!

November 24, 2019

Congrats to everyone involved in our latest publication:

Congratulations SafineAI!

October 27, 2019

SafineAI, a new start-up based on technology developed by the Computational Optics Lab, has been awarded the Microsoft Start-up Prize at Duke University.

Monthly update - September 2019

October 1, 2019

The Horstmeyer Lab is beginning work on two new grants!

1. A Duke Coulter Foundation award, aimed at creating a better microscope for rapid imaging cytopathology slides.

Monthly update - August 2019

September 5, 2019

The school year has now begun and Dr.

Monthly update - July 2019

August 1, 2019

A number of students have been busy in the lab this summer, making some great progress on their experiments. Here's a few highlights from what we've accomplished:

1. We have put the finishing touches on our lab's first official paper! Hopefully there will be many more to come. 

Monthly update - June 2019

July 1, 2019

I'll try to post monthly updates from here on out. Here's what the Computational Optics Lab has been up to this June: